Use of Smartphone Applications in Post-Mastectomy Breast Cancer Patients: A Literature Review
Keywords:
breast cancer, post-mastectomy, quality of life, smartphone applications, symptom managementAbstract
Post-mastectomy breast cancer patients frequently experience physical and psychological symptoms, including pain, fatigue, limited mobility, body image disturbance, and emotional distress that negatively affect quality of life. Smartphone applications have emerged as digital strategies to support symptom management and patient engagement during recovery. This study aimed to analyze the use of smartphone applications among post-mastectomy breast cancer patients through a literature review. Articles were retrieved from PubMed, Scopus, ScienceDirect, SAGE, and Google Scholar. A total of 342 articles were found during the search, with publication years ranging from 2021 to 2025. Of these, 11 studies that met the inclusion criteria were analyzed based on research design and symptom-related outcomes. The findings indicate that smartphone applications improve symptom monitoring through electronic patient-reported outcomes (ePRO), enhance self-efficacy, and reduce psychological distress and anxiety. Several studies also reported improvements in quality of life and adherence to rehabilitation programs. However, evidence regarding long-term physical symptom improvement remains inconsistent. In conclusion, smartphone applications serve as effective supportive interventions for symptom management and recovery among post-mastectomy breast cancer patients, although further standardized and long-term studies
References
Akingbade, O., Hong, KY, Ayo, OS, Alade, AS, Lawal, MA, Somoye, IE, Adediran, V., Sado, O., & Chow, KM (2024). Development and feasibility of an mHealth intervention for psychoeducational support of Nigerian women diagnosed with breast cancer undergoing chemotherapy: A pilot randomized controlled trial. PLOS ONE, 19(1), e0314365. https://doi.org/10.1371/journal.pone.0314365
Boniface, J. De, Szulkin, R., & Johansson, ALV (2023). Medical and surgical postoperative complications after breast conservation versus mastectomy in older women with breast cancer : Swedish population-based register study of 34 139 women. British Journal of Surgery , 110 (3), 344–352. https://doi.org/10.1093/bjs/znac411
Borosund, E., Ehlers, S.L., Varsi, C., Clark, M.M., Andrykowski, M.A., Cvancarova, M., & Solberg, L. (2020). Results from a randomized controlled trial testing StressProffen ; an application-based stress-management intervention for cancer survivors. Cancer Medicine , January , 3775–3785. https://doi.org/10.1002/cam4.3000
Cahyono, HD, Irawaty, D., & Adam, M. (2022). The effect of Benson relaxation application (“ Bens app”) on reducing fatigue in patients with breast cancer undergoing chemotherapy: A quasi-experimental study. Belitung Nursing Journal, 8(4), 304–310. https://doi.org/10.33546/bnj.1843
Grasič Kuhar, C., Privšek, N., Sraka, M., Grasič, E., Kovac, T., & Kukar, M. (2025). Patients' daily reporting of symptoms via mobile application reveals a significant difference between patients' perceptions and doctors' interpretations. Frontiers in Oncology, 15, 1595322. https://doi.org/10.3389/fonc.2025.1595322
Hansen, S.T., Piil, K., Hansen, L.B., Ledertoug, K.M., Hølge-Hazelton, B., & Schmidt, V.J. (2022). Electronic patient-reported outcome measures to enable systematic follow-up in treatment and care of women diagnosed with breast cancer: A feasibility study protocol. BMJ Open, 12(11), e065110. https://doi.org/10.1136/bmjopen-2022-065110
Jiang, L., Xu, J., Wu, Y., Liu, Y., Wang, X., & Hu, Y. (2024). Effects of the “AI-TA” mobile app with intelligent design on psychological and related symptoms of young survivors of breast cancer: Randomized controlled trial. JMIR mHealth and uHealth, 12, e50783. https://doi.org/10.2196/50783
Keikha, Maserat, L., Elham, Zeinab, & Mohammadzadeh. (2022). Telerehabilitation and Monitoring Physical Activity in Patients with Breast Cancer: Systematic Review. Iranian Journal of Nursing and Midwifery Research . https://doi.org/10.4103/ijnmr.ijnmr
Kim, S.M., Kim, D.S., Jang, Y., Kim, MK, Yu, E.S., Han, D.H., & Kim, H.J. (2025). Evaluating the effectiveness of a mobile app for breast cancer self-management on self-efficacy: Nonrandomized intervention trial. JMIR mHealth and uHealth, 13, e63989. https://doi.org/10.2196/63989
Lee, EG, Lee, DE, Kim, J., Han, J., Lee, S., Kang, HS, Lee, ES, Chae, H., Sim, SH, Lee, KS, Lee, J., Lee, HJ, Yoo, JS, Wie, GA, & Jung, SY (2025). Impact of a 24-week mobile app–based human coaching program on body composition and lipid metabolism in breast cancer survivors with overweight or obesity: Single-arm prospective cohort study. JMIR mHealth and uHealth, 13, e64846. https://doi.org/10.2196/64846
Lim, J.Y., Kim, J.K., Kim, Y., Ahn, S.Y., Yu, J., & Hwang, J.H. (2021). A modular mobile health app for personalized rehabilitation throughout the breast cancer care continuum: Development study. JMIR Formative Research, 5(4), e23304. https://doi.org/10.2196/23304
National Center for Biotechnology Information. (2021). Mastectomy . https://www.ncbi.nlm.nih.gov/
Paalim, K., Virtanen, M., Henner, A., & Nieminen, M. T. (2022). Effectiveness of Digital Counseling Environments on Anxiety, Depression, and Adherence to Treatment Among Patients Who Are Chronically Ill: Systematic Review Corresponding Author: Journal of Medical Internet Research , 24 . https://doi.org/10.2196/30077
Qin, M., Chen, B., Sun, S., & Liu, X. (2022). Effect of Mobile Phone App – Based Interventions on Quality of Life and Psychological Symptoms Among Adult Cancer Survivors : Systematic Review and Meta-analysis of Randomized Controlled Trials Corresponding Author : Journal of Medical Internet Research , 24 , 1–22. https://doi.org/10.2196/39799
Shi, N., Wong, AKC, Wong, FKC, & Sha, L. (2023). Mobile health application–based interventions to improve self-management of chemotherapy-related symptoms among people with breast cancer who are undergoing chemotherapy: A systematic review. The Oncologist, 28(4), e175–e182. https://doi.org/10.1093/oncolo/oyac267
Shi, N., Wong, AKC, Wong, FKC, Zhang, N., Zhu, W., Shen, K., Lai, X., Jin, Y., Gu, C., Nie, L., & Dong, X. (2024). Feasibility of a mobile health app–based self-management program for Chinese patients with breast cancer receiving chemotherapy: A randomized controlled pilot study. Digital Health, 10, 20552076241231560. https://doi.org/10.1177/20552076241231560
Suchodolska, G., & Senkus, E. (2022). Mobile applications for early breast cancer chemotherapy-related symptoms reporting and management: A scoping review. Cancer Treatment Reviews, 105, 102364. https://doi.org/10.1016/j.ctrv.2022.102364
Tian, L., Wen, Y., Li, T., Liu, C., & Fan, J. (2025). Effects of using app-based interventions on quality of life among breast cancer patients: A systematic review with meta-analysis. Annals of Medicine, 57(1), 2499027. https://doi.org/10.1080/07853890.2025.2499027
Vangsness, K.L., Juste, J., Sam, A., Munabi, N., Chu, M., Agko, M., Chang, J., & Carre, A.L. (2024). Post-Mastectomy Breast Reconstruction Disparities: A Systematic Review of Sociodemographic and Economic Barriers. Medicina , 1–18.
Zhang, T., Feng, W., Sun, Y., Li, Y., Hu, J., Du, X., Lai, L., Ke, Y., Hui, BPH, & Ren, Z. (2025). Feasibility, acceptability, and effectiveness of an asynchronous, internet-delivered acceptance and commitment therapy for people living with cancer: A pilot randomized controlled trial using mixed methods. Computers in Human Behavior Reports, 20, 100859. https://doi.org/10.1016/j.chbr.2025.100859.




